Merck 104350 0500 Histidine Monohydrochloride Monohydrate For Biochemistry 500 GR.

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Description
Catalogue Number	104350
Synonyms	His

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Product Information
CAS number	5934-29-2
EC number	211-438-9
Hill Formula	C₆H₁₀ClN₃O₂ * H₂O
Molar Mass	209.63 g/mol
HS Code	2933 29 90
Structure formula Image
Quality Level	MQ100

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Applications
Application	L-Histidine monohydrochloride monohydrate for biochemistry. CAS 5934-29-2, pH 3.5 - 4.5 (100 g/l, H₂O, 20 °C).

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Physicochemical Information
Density	1.4723 g/cm3 (20 °C)
Melting Point	256 - 268 °C (decomposition)
pH value	4.38 - 4.48 (149.55 g/l, H₂O, 20 °C)
Vapor pressure	<0.1 hPa (20 °C)
Bulk density	770 kg/m3
Solubility	149.55 g/l

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Safety Information according to GHS
RTECS	MS3119000
Storage class	10 - 13 Other liquids and solids
WGK	WGK 1 slightly hazardous to water
Disposal	3\nRelatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

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Storage and Shipping Information
Storage	Store below +30°C.

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Specifications
Assay (calculated on dried substance)	99.0 - 101.0 %
Identity (IR-spectrum)	passes test
Identity (wet chemistry)	passes test
Appearance	white to almost white crystalline powder or colorless crystals
Appearance of solution (50 g/l CO₂-free water)	clear and not more intense in color than reference solution BY₆
Spec. rotation (α 20/D, 110 g/l, hydrochloric acid 120 g/l, calc. on dried substance)	+9.2 to +10.6
Sulfate (SO₄)	≤ 200 ppm
Heavy metals (as Pb)	≤ 10 ppm
As (Arsenic)	≤ 5 ppm
Ca (Calcium)	≤ 10 ppm
Co (Cobalt)	≤ 5 ppm
Fe (Iron)	≤ 5 ppm
K (Potassium)	≤ 5 ppm
Mg (Magnesium)	≤ 5 ppm
Na (Sodium)	≤ 50 ppm
Zn (Zinc)	≤ 5 ppm
Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)	≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm))	≤ 0.02 %
Ninhydrin-positive substances (LC) (total impurities)	≤ 0.5 %
Loss on drying (150 °C)	7.0 - 10.0 %