Merck 107478 2500 1,2-Propanediol Suitable Emprove 2,5 LT.

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Description
Catalogue Number	107478
Synonyms	1,2-Propylene glycol
Description	1,2-Propanediol

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Product Information
CAS number	57-55-6
EC number	200-338-0
Grade	Ph Eur,BP,USP
Hill Formula	C₃H₈O₂
Chemical formula	CH₃CH(OH)CH₂OH
Molar Mass	76.09 g/mol
HS Code	2905 32 00
Structure formula Image
Quality Level	MQ500

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Physicochemical Information
Boiling point	188 °C (1013 hPa)
Density	1.036 g/cm3 (25 °C)
Explosion limit	2.4 - 17.4 %(V)
Flash point	99 °C
Ignition temperature	371 °C
Melting Point	-59 °C
pH value	6 - 8 (100 g/l, H₂O, 20 °C)
Vapor pressure	0.2 hPa (25 °C)
Refractive Index	1.43 (20 °C)

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Toxicological Information
LD 50 oral	LD50 Rat 19400 - 36000 mg/kg
LD 50 dermal	LD50 Rabbit 20800 mg/kg

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Safety Information according to GHS
RTECS	TY2000000
Storage class	10 - 13 Other liquids and solids
WGK	WGK 1 slightly hazardous to water
Disposal	3\nRelatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

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Storage and Shipping Information
Storage	Store at +2°C to +30°C.

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Specifications
Purity (GC)	≥ 99.5 %
Identity (IR)	conforms
Identity D (Ph Eur)**	121 - 128 °C
Appearance of the substance	conforms
Density (d 20 °C/20 °C)	1.035 - 1.040
Density (d 25 °C/25 °C)	1.035 - 1.037
Refractive index (n 20/D)	1.431 - 1.433
Boiling point	184 - 189 °C
Acidity	conforms
Chloride (Cl)	≤ 0.007 %
Sulfate (SO₄)	≤ 0.006 %
Isomers of dipropylene glycol	conforms
Diethylene glycol (GC)	≤ 0.10 %
Ethylenglycol (GC)	≤ 0.10 %
Residual solvents (ICH Q3C)	excluded by production process
Oxidizing Substances	conforms
Reducing substances	conforms
Sulfated ash	≤ 0.007 %
Water	≤ 0.20 %
Bacterial endotoxins	≤ 2.5 I.U./ml
Total aerobic microbial count (TAMC)	≤ 10²
Total combined yeasts/moulds count (TYMC)	≤ 10¹
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).\nClass 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).\n**The value of the additional identity test is transferred from the supplier CoA.\nConforms to Ph Eur, BP, USP